Small interfering RNA (siRNA) is a class of double-stranded RNA molecules, 20-25 base pairs in length, that play a crucial role in the RNA interference (RNAi) pathway, where they interfere with the expression of specific genes with complementary nucleotide sequences. This mechanism is widely used in research and therapeutic applications to silence genes and study gene function or treat diseases by targeting and degrading mRNA molecules before they can be translated into proteins.

SiRNA

Small interfering RNA (siRNA) is a class of double-stranded RNA molecules, typically 20-25 base pairs in length, that play a critical role in the RNA interference (RNAi) pathway by targeting and degrading complementary mRNA sequences, thus silencing gene expression. This mechanism is harnessed in research and therapeutic applications to selectively inhibit the expression of specific genes, offering potential treatments for various diseases, including viral infections and cancer.

Small Interfering RNA

Double-stranded RNA (dsRNA) is a molecular structure consisting of two complementary strands of RNA that play a critical role in cellular processes and immune responses. It is a key trigger for RNA interference, a biological process used by cells to regulate gene expression and defend against viral infections.

Double-stranded RNA

RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression or translation, effectively silencing targeted gene activity. This mechanism is crucial for regulating gene expression, defending against viral infections, and has potential applications in gene therapy and research.

RNA Interference

RNAi pathway

Gene expression is the process by which information from a gene is used to synthesize a functional gene product, typically proteins, which ultimately determine cellular function and phenotype. This process is tightly regulated at multiple levels, including transcription, RNA processing, translation, and post-translational modifications, to ensure proper cellular function and response to environmental cues.

Gene Expression

Complementary nucleotide sequences

Research Applications

Therapeutic applications refer to the use of various treatments, including drugs, therapies, and technologies, to alleviate symptoms, cure diseases, or improve the quality of life for patients. These applications are grounded in scientific research and clinical trials to ensure safety and efficacy in addressing specific medical conditions.

Therapeutic Applications

Silence genes

Gene function refers to the specific role a gene plays in the biological processes of an organism, often through the production of proteins or RNA molecules that influence cellular structure, function, and regulation. Understanding gene function is crucial for elucidating the mechanisms of genetic diseases, development, and evolutionary biology.

Concepts

Relevant Degrees

Your Lessons