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Pathophysiology Of SIRS
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Summary
The pathophysiology of
Systemic Inflammatory Response Syndrome
(SIRS) involves a
Dysregulated inflammatory response
to a variety of
Clinical insults
, leading to
Widespread tissue damage
and
Organ Dysfunction
. This process is characterized by the release of
Pro-inflammatory Cytokines
,
Activation of the complement system
, and
Endothelial Dysfunction
, which collectively contribute to the
Systemic manifestations of the syndrome
.
Concepts
Cytokine Storm
Endothelial Dysfunction
Complement System Activation
Pro-inflammatory Cytokines
Acute Phase Response
Toll-like Receptors
Oxidative Stress
Coagulation Cascade
Immune Dysregulation
Multiple Organ Dysfunction Syndrome (MODS)
Systemic Inflammatory Response Syndrome
Relevant Degrees
Special Pathology 40%
Pathological Physiology 30%
Poisoning and Intoxication 20%
Systematic Physiology 10%
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