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Concept
ASC Protein
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Summary
ASC Protein
, also known as
Apoptosis-associated Speck-like protein
containing a CARD, is crucial in the formation of
inflammasomes
, which are
Multiprotein complexes
involved in the activation of
Inflammatory Responses
. It acts as an
Adaptor protein
, bridging the interaction between NLRP3 and pro-caspase-1, facilitating the
Maturation of pro-inflammatory cytokines
like IL-1β and IL-18.
Concepts
Inflammasome
NLRP3
Pro-caspase-1
IL-1β
IL-18
Apoptosis
CARD Domain
Innate Immunity
Protein-protein Interaction
Inflammatory Response
Caspase-1 Activation
Relevant Degrees
Biochemistry and Molecular Biology 50%
Neurology 30%
General Toxicology 20%
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