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IL-18
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Summary
IL-18 is a
Pro-inflammatory cytokine
that plays a crucial role in both innate and
Adaptive immune responses
, often working in synergy with IL-12 to induce
IFN-gamma production
. It is involved in various inflammatory and
Autoimmune Diseases
, making it a target for
Therapeutic Interventions
aimed at
Modulating the immune system
.
Concepts
Cytokines
Interferon-gamma
Innate Immunity
Adaptive Immunity
Inflammation
Autoimmune Diseases
IL-12
Therapeutic Targeting
Immune Modulation
Pro-inflammatory Response
Caspase-1 Activation
NOD-like Receptor (NLR) Family
ASC Protein
Relevant Degrees
Pathological Physiology 100%
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