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NLRP3
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Summary
NLRP3 is a crucial component of the
Innate Immune System
, acting as a sensor that detects a wide range of
Pathogenic and stress signals
to initiate the formation of the inflammasome, a
Multiprotein complex
that activates
Inflammatory Responses
.
Dysregulation of NLRP3
is implicated in various
Inflammatory Diseases
, making it a significant target for
Therapeutic Interventions
.
Concepts
Innate Immunity
Inflammasome
Pattern Recognition Receptors
Inflammation
Caspase-1 Activation
Pyroptosis
Autoinflammatory Diseases
Mitochondrial Dysfunction
Reactive Oxygen Species
Therapeutic Targeting
ASC Protein
Relevant Degrees
Biochemistry and Molecular Biology 40%
Pathology and Disease 30%
Microbiology 20%
Physiology 10%
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