Serum IgG4 levels are often measured to diagnose and monitor IgG4-related disease, a condition characterized by inflammation and fibrosis in various organs. Elevated IgG4 levels can also be seen in other autoimmune and allergic conditions, making it crucial to interpret them in the context of clinical presentation and other diagnostic tests.

Serum IgG4 Levels

Diagnose IgG4-related disease

Monitor IgG4-related disease

IgG4-related Disease is a systemic condition characterized by the infiltration of IgG4-positive plasma cells into various organs, leading to organ enlargement, fibrosis, and dysfunction. It often mimics other inflammatory and neoplastic conditions, making accurate diagnosis critical for effective treatment with corticosteroids or immunosuppressive agents.

IgG4-related Disease

Inflammation and fibrosis

Various organs

Elevated IgG4 levels

Autoimmune conditions occur when the immune system mistakenly attacks the body's own healthy cells, perceiving them as threats. These disorders can affect any part of the body, leading to chronic inflammation and tissue damage, and often require lifelong management to control symptoms and prevent complications.

Autoimmune Conditions

Allergic conditions

Context of clinical presentation

Diagnostic tests are essential tools in healthcare used to detect, diagnose, and monitor diseases or conditions, guiding treatment decisions and patient management. Their accuracy, reliability, and relevance are critical to ensuring effective clinical outcomes and minimizing potential risks associated with misdiagnosis or unnecessary interventions.

Concepts

Relevant Degrees

Your Lessons