Preformulation studies are the initial phase of pharmaceutical development, focusing on the physicochemical properties of a drug candidate to guide formulation and delivery method decisions. These studies are essential for understanding a drug's stability, solubility, and compatibility with other ingredients, ultimately influencing its efficacy and safety profile.

Preformulation Studies

Initial phase of pharmaceutical development

Physicochemical Properties

Drug candidate

Formulation and delivery method decisions

Drug stability refers to the ability of a pharmaceutical product to maintain its identity, strength, quality, and purity throughout its shelf life. It is crucial for ensuring safety and efficacy, influencing factors such as storage conditions, formulation, and packaging.

Drug Stability

Drug solubility is a critical factor in pharmaceutical development as it affects the absorption, distribution, metabolism, and excretion of a drug, ultimately influencing its bioavailability and therapeutic effectiveness. Enhancing solubility can be achieved through various formulation strategies, including the use of solubilizing agents, particle size reduction, and chemical modification.

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