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Concept
G1 Phase Arrest
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Summary
G1 Phase Arrest
is a
Cellular mechanism
that halts the
Cell Cycle
in the G1 phase, preventing progression to
DNA Synthesis
in the
S Phase
, often in response to
DNA Damage
or other
Stress Signals
. This process is crucial for maintaining
Genomic Stability
and preventing the propagation of
Damaged DNA
, which could lead to cancer or
Other diseases
.
Concepts
Cell Cycle
DNA Damage Response
Checkpoint Proteins
Cyclin-dependent Kinases
Retinoblastoma Protein
Tumor Suppressor Genes
P53 Pathway
Cell Cycle Regulation
Apoptosis
Genomic Stability
Cell Cycle Inhibition
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