Genomic stability refers to the maintenance of DNA sequence and chromosomal integrity across cell divisions, ensuring proper cellular function and preventing diseases such as cancer. It is achieved through a range of cellular mechanisms that repair DNA damage, regulate cell cycle checkpoints, and maintain telomere length.

Genomic Stability

Genomic stability

A DNA sequence is a specific linear arrangement of nucleotides (adenine, thymine, cytosine, and guanine) that encodes the genetic information of an organism. This sequence determines the synthesis of proteins and regulates various biological processes, impacting traits and functions at the cellular and organismal levels.

DNA sequence

chromosomal integrity

cell divisions

Cellular function encompasses the myriad activities carried out by cells to maintain homeostasis, facilitate growth, and ensure survival. It involves complex interactions between cellular structures and biochemical pathways to perform tasks such as energy production, molecular transport, and signal transduction.

cellular function

diseases such as cancer

cellular mechanisms

repair DNA damage

regulate cell cycle checkpoints

maintain telomere length

Maintaining Genomic Stability Through DNA Helicases

Mechanisms of Off-Target Effects

The Process of Nucleotide Excision Repair

Relevant Degrees

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