Eukaryotic Initiation Factor 4 (eIF4) is a complex essential for the initiation phase of eukaryotic translation, facilitating the recruitment of the ribosome to the mRNA. It plays a critical role in unwinding RNA secondary structures, enhancing mRNA stability and accessibility for effective protein synthesis.

Eukaryotic Initiation Factor 4

EIF4

Initiation phase of eukaryotic translation

Recruitment of the ribosome

Messenger RNA (mRNA) is a type of RNA that carries genetic information from DNA to the ribosome, where proteins are synthesized. It plays a crucial role in the process of gene expression, acting as a template for translating genetic code into functional proteins.

MRNA

RNA secondary structures

mRNA stability is crucial for regulating gene expression levels, as it determines the lifespan of mRNA molecules in the cell, thereby influencing protein synthesis. Factors such as sequence elements, RNA-binding proteins, and microRNAs play significant roles in modulating mRNA decay and stability, impacting cellular responses and development.

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