Depot Medroxyprogesterone Acetate (DMPA) is a long-acting, Reversible contraceptive injection that prevents pregnancy by Inhibiting ovulation, Thickening cervical mucus, and Altering the endometrium. It is administered every 12 to 14 weeks and is highly effective, but may cause side effects such as Weight Gain, Menstrual Irregularities, and a potential Delay in the return of fertility after discontinuation.