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Concept
Antifolates
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Summary
Antifolates are a
Class of drugs
that inhibit the function of
Folic Acid
, a
Vitamin essential for DNA synthesis
and
Cell Division
, making them effective in
Treating certain cancers
and
Bacterial Infections
. By targeting the
Folate pathway
, antifolates disrupt the
Proliferation of rapidly dividing cells
, thus serving as crucial agents in chemotherapy and
Antimicrobial Therapy
.
Concepts
Folic Acid Metabolism
DNA Synthesis
Cell Cycle Inhibition
Chemotherapy
Antimicrobial Therapy
Dihydrofolate Reductase
Methotrexate
Pyrimethamine
Trimethoprim
Resistance Mechanisms
Antimalarial Drugs
Relevant Degrees
Medicaments According to Origin 75%
Medicaments According to Principal Action 13%
Pathological Physiology 13%
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