A paradigm shift refers to a fundamental change in the underlying assumptions or methodologies within a scientific discipline or other structured framework. It often results in new ways of thinking and can lead to significant advancements or transformations in understanding and practice.
Transformational change refers to a profound, systemic shift that fundamentally alters the culture, operations, and outcomes of an organization or system. It is often driven by visionary leadership and requires a comprehensive approach that engages all stakeholders to achieve sustainable, long-term improvements.