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Concept
A genotype is the genetic makeup of an organism, representing the specific alleles present at a particular set of genes. It is a crucial determinant of an organism's phenotype, which is the observable expression of the genetic information in conjunction with environmental influences.
Concept
A phenotype is the set of observable characteristics or traits of an organism, resulting from the interaction of its genotype with the environment. It encompasses physical appearance, development, biochemical properties, and behavior, and is a critical concept in understanding how genetic and environmental factors influence an organism's traits.
Heritability is a statistical estimate that measures the proportion of observed variation in a particular trait among individuals in a population that can be attributed to genetic differences. It is important to note that heritability does not indicate the extent to which a trait is genetically determined in an individual, nor does it imply immutability of the trait in response to environmental changes.
Genetic variation refers to the differences in DNA sequences among individuals within a population, which is crucial for evolution and adaptation to changing environments. It arises from mutations, genetic recombination during sexual reproduction, and gene flow between populations, providing the raw material for natural selection to act upon.
Concept
Alleles are different versions of the same gene that can exist at a specific locus on a chromosome, influencing an organism's traits by varying the expression of that gene. The combination of alleles inherited from both parents determines the organism's genotype and can result in diverse phenotypic outcomes, including dominant, recessive, and co-dominant expressions.
Polygenic traits are characteristics influenced by multiple genes, often resulting in a continuous distribution of phenotypes, such as height or skin color. These traits are typically influenced by both genetic and environmental factors, making their inheritance patterns complex and multifactorial.
Gene-environment interaction refers to the phenomenon where the effects of genes on a trait are dependent on specific environmental factors, and vice versa. This interaction underscores the complexity of phenotypic expression, as it highlights that neither genetic nor environmental factors alone can fully account for an individual's characteristics.
Single Nucleotide Polymorphisms (SNPs) are variations at a single position in a DNA sequence among individuals, which can serve as biological markers to identify genes associated with disease. SNPs are the most common type of genetic variation among people, influencing how humans develop diseases and respond to pathogens, chemicals, drugs, vaccines, and other agents.
Epigenetics refers to the study of heritable changes in gene expression that do not involve alterations to the underlying DNA sequence. These changes are influenced by various factors including environment, lifestyle, and disease, and can have significant implications for development, health, and evolution.
Mendelian inheritance refers to the set of principles regarding the transmission of genetic traits from parents to offspring, formulated by Gregor Mendel through his work with pea plants. These principles include the segregation and independent assortment of alleles, which explain the predictable patterns of inheritance observed in organisms with sexually reproducing diploid genomes.
Genetic linkage refers to the tendency of genes located close to each other on the same chromosome to be inherited together during meiosis, as they are less likely to be separated by recombination. This phenomenon is crucial for understanding inheritance patterns and is used in mapping genetic diseases and traits.
Individual characteristics refer to the unique traits and qualities that distinguish one person from another, encompassing a wide range of psychological, biological, and social factors. These characteristics influence behaviors, preferences, and interactions, playing a crucial role in shaping personal identity and life experiences.
Environmental influences on bone development encompass a variety of factors, including nutrition, physical activity, and exposure to toxins, which can significantly affect bone density, growth, and overall skeletal health. These factors interact with genetic predispositions to shape bone architecture and strength throughout an individual's life, particularly during critical growth periods such as childhood and adolescence.
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