Sec13 is a protein that plays a crucial role in the formation of COPII vesicles, which are essential for the transport of proteins from the endoplasmic reticulum to the Golgi apparatus. It is a component of the COPII coat complex, which facilitates the budding and scission of transport vesicles in cellular trafficking processes.
COPII vesicles are essential transport carriers that mediate the export of proteins and lipids from the endoplasmic reticulum to the Golgi apparatus. They are formed by the sequential recruitment of coat proteins, which drive membrane curvature and cargo selection, facilitating efficient intracellular transport and secretion processes.
The Sec23/Sec24 complex is a crucial component of the COPII coat involved in the transport of proteins from the endoplasmic reticulum to the Golgi apparatus. It plays a pivotal role in cargo selection and vesicle formation, ensuring proper cellular functioning and protein trafficking.