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The quadruple screen test is a prenatal blood test that evaluates the risk of certain birth defects by measuring four substances in the mother's blood: alpha-fetoprotein, human chorionic gonadotropin, unconjugated estriol, and inhibin A. It is typically performed during the second trimester of pregnancy and helps assess the likelihood of conditions such as Down syndrome, trisomy 18, and neural tube defects.
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