The Protein Data Bank (PDB) is a comprehensive, publicly accessible database of 3D structural data of biological macromolecules, crucial for understanding the molecular basis of biological activity. It serves as an essential resource for researchers across disciplines, facilitating advances in fields such as drug design, structural biology, and bioinformatics.

Protein Data Bank

3D structural data

Biological macromolecules are large, complex molecules that are critical for life, serving as the building blocks of cells and performing a wide range of functions essential to biological processes. They include proteins, nucleic acids, carbohydrates, and lipids, each with unique structures and roles in cellular activities such as catalysis, genetic information storage, energy provision, and structural support.

Biological Macromolecules

Molecular basis of biological activity

Drug design is the process of discovering and developing new medications based on the knowledge of a biological target. It involves the use of computational tools to predict how a drug interacts with its target and optimize its efficacy and safety profile.

Drug Design

Structural biology is a branch of molecular biology concerned with the study of the molecular structure and dynamics of biological macromolecules, particularly proteins and nucleic acids. Understanding these structures helps elucidate the function of molecules, facilitating advancements in drug design and biotechnology.

Structural Biology

Bioinformatics is an interdisciplinary field that combines biology, computer science, and information technology to analyze and interpret biological data, particularly large datasets such as genomic sequences. It plays a crucial role in understanding complex biological processes and advancing personalized medicine by enabling the integration of vast amounts of data to uncover insights into genetic and molecular mechanisms.

Concepts

Relevant Degrees

Your Lessons