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Plasmid Addiction System
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Summary
A
Plasmid Addiction System
is a
Genetic mechanism
that ensures the
Retention of plasmids
in a host cell by encoding a
Toxin-antitoxin pair
, where the antitoxin is less stable than the toxin. This results in
Cell Death
if the plasmid is lost, as the antitoxin degrades faster than the toxin, ensuring only
Plasmid-containing cells
survive.
Concepts
Toxin-antitoxin System
Plasmid Stability
Post-segregational Killing
Antitoxin Degradation
Cell Survival
Genetic Retention
Plasmid Inheritance
Molecular Biology
Bacterial Genetics
Selective Pressure
Plasmid Maintenance
Relevant Degrees
Biochemistry and Molecular Biology 47%
Microbiology 35%
General Toxicology 18%
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