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Concept
Pathological Processes
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Concept
Mesenchymal Transition
Mesenchymal transition
refers to the process by which
epithelial cells
lose their
cell polarity
and
cell-cell adhesion
, gaining migratory and
invasive properties
to become
mesenchymal stem cells
. This transformation is crucial for
embryonic development
, tissue regeneration, and
cancer metastasis
, highlighting its dual role in both physiological and
pathological contexts
.
3