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Concept
Mesenchymal Transition
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Summary
Mesenchymal Transition
refers to the process by which
Epithelial Cells
lose their
Cell Polarity
and
Cell-Cell Adhesion
, gaining migratory and
Invasive Properties
to become
Mesenchymal Stem Cells
. This transformation is crucial for
Embryonic Development
,
Tissue Regeneration
, and
Cancer Metastasis
, highlighting its dual role in both physiological and
Pathological contexts
.
Concepts
Epithelial-mesenchymal Transition (EMT)
Cell Polarity
Cell-Cell Adhesion
Mesenchymal Stem Cells
Tissue Regeneration
Cancer Metastasis
Embryonic Development
Pathological Processes
Physiological Processes
Invasive Properties
Migratory Properties
N-cadherin
Endocardial Cushion Formation
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