Nonribosomal Peptide Synthesis is a process by which certain microorganisms produce Bioactive peptides without the use of ribosomes, utilizing Large enzyme complexes called Nonribosomal peptide synthetases (NRPS). This method allows for the incorporation of a wide variety of Building Blocks, including Non-standard amino acids, leading to structurally diverse and Functionally potent compounds such as antibiotics and immunosuppressants.