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Concept
Non-mevalonate Pathway
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Summary
The
Non-mevalonate Pathway
, also known as the
MEP/DOXP Pathway
, is an
Alternative metabolic route
used by bacteria, algae, and plants for the
Biosynthesis of isoprenoids
, which are
Essential for various cellular functions
. This pathway is of significant interest for antibiotic and
Antimalarial Drug Development
due to its
Absence in humans
, making it a potential target for
Selective Inhibition
without
Affecting human cells
.
Concepts
Isoprenoid Biosynthesis
MEP/DOXP Pathway
2-C-methyl-D-erythritol 4-phosphate
Deoxyxylulose Phosphate
Antibiotic Target
Antimalarial Drug Development
Enzyme Inhibition
Metabolic Pathway
Bacterial Metabolism
Plant Metabolism
Isopentenyl Pyrophosphate
Relevant Degrees
Biochemistry and Molecular Biology 50%
Organic Chemistry 30%
Pharmacology and Therapeutics 20%
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