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Müllerian agenesis, also known as Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome, is a congenital disorder characterized by the underdevelopment or absence of the uterus and upper two-thirds of the vagina in genetically female individuals. Despite these reproductive anomalies, affected individuals typically have normal ovarian function and secondary sexual characteristics, leading to primary amenorrhea as a common presenting symptom.
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