Translocase of the outer membrane (TOM complex) is a crucial protein complex in mitochondria responsible for the recognition and import of precursor proteins from the cytosol into the mitochondrial intermembrane space. It serves as the primary entry gate for most mitochondrial proteins, ensuring proper mitochondrial function and biogenesis.
Mitochondrial protein import is a crucial cellular process where proteins synthesized in the cytosol are transported into the mitochondria to maintain its function and biogenesis. This process involves multiple pathways and protein complexes that recognize, translocate, and fold these proteins within the mitochondrial membranes and matrix.