The medulla of the thymus is a critical region within the thymus gland, playing a pivotal role in the maturation and selection of T-cells, ensuring they can distinguish between self and non-self antigens. This area is characterized by the presence of Hassall's corpuscles, which are involved in the regulatory mechanisms of T-cell development and the elimination of autoreactive T-cells.

Medulla Of Thymus

The medulla of the thymus is the central part of the thymus gland, crucial for the maturation of T-lymphocytes and the establishment of self-tolerance to prevent autoimmune diseases. It contains a unique structure called Hassall's corpuscles, which play a role in the regulation of immune responses.

Medulla Of The Thymus

The thymus gland is a vital component of the immune system, responsible for the maturation of T-cells, which are crucial for adaptive immunity. Located in the upper chest, it is most active during childhood and gradually shrinks after puberty, but its role in immune function remains significant throughout life.

Thymus Gland

Maturation of T-cells

Selection of T-cells

Self and non-self antigens

Hassall's corpuscles are unique structures found in the medulla of the thymus, playing a crucial role in the maturation of T-cells and the establishment of central immune tolerance. They are composed of concentric layers of epithelial cells and are involved in the development of regulatory T-cells, which help prevent autoimmune responses.

Concepts

Your Lessons