Immune tolerance in pregnancy is a crucial physiological process where the maternal immune system adapts to prevent rejection of the genetically distinct fetus while still protecting against infections. This involves a complex interplay of immune cells, cytokines, and regulatory pathways to maintain a balance between immune tolerance and defense.

Immune Tolerance In Pregnancy

Immune tolerance is the immune system's ability to recognize and not attack the body's own cells and harmless substances, preventing autoimmune diseases and allergies. This process involves complex mechanisms that ensure self-tolerance and prevent immune responses against beneficial or neutral antigens.

Immune Tolerance

Pregnancy is the biological process in which a fertilized egg develops into a fetus within a woman's uterus, typically lasting about 40 weeks from the last menstrual period to childbirth. It involves complex physiological changes and requires careful medical monitoring to ensure the health of both the mother and the developing baby.

Pregnancy

Maternal immune system

Rejection of the genetically distinct fetus

Protection against infections

Complex interplay of immune cells

Cytokines are small proteins crucial for cell signaling in the immune system, acting as mediators and regulators of immunity, inflammation, and hematopoiesis. They can be pro-inflammatory or anti-inflammatory and play a significant role in the body's response to infection, disease, and trauma.

Cytokines

Regulatory pathways are structured processes that govern the approval and oversight of products, particularly in fields like pharmaceuticals and biotechnology, ensuring they meet safety and efficacy standards. These pathways involve multiple stages of evaluation and compliance with legal and scientific requirements to protect public health and facilitate innovation.

Concepts

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