IgA nephropathy, also known as Berger's disease, is a kidney disorder characterized by the deposition of IgA antibodies in the glomeruli, leading to inflammation and potential kidney damage. It is the most common form of glomerulonephritis worldwide, often presenting with hematuria and proteinuria, and can progress to chronic kidney disease if not properly managed.

IgA Nephropathy

Berger's disease

Kidney Disorder

Deposition of IgA antibodies

Glomeruli are tiny structures within the kidneys that play a crucial role in filtering blood to form urine. They are essential for maintaining fluid and electrolyte balance, as well as for the excretion of waste products from the body.

Glomeruli

Inflammation is the body's complex biological response to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective attempt to remove the injurious stimuli and initiate the healing process. While acute inflammation is a vital part of the immune response, chronic inflammation can contribute to various diseases, including arthritis, cardiovascular diseases, and certain cancers.

Inflammation

Potential kidney damage

Common form of glomerulonephritis

Hematuria is the presence of blood in the urine, which can be a sign of a wide range of medical conditions, from benign to serious. It requires thorough evaluation to determine the underlying cause, which can include urinary tract infections, kidney stones, or more severe issues like cancer.

Hematuria

Proteinuria is a condition characterized by an abnormal amount of protein in the urine, often indicating kidney damage or disease. It can be a sign of underlying health issues such as diabetes, hypertension, or glomerulonephritis, and requires medical evaluation to determine the cause and appropriate treatment.

Proteinuria

Chronic kidney disease (CKD) is a progressive condition characterized by the gradual loss of kidney function over time, which can lead to end-stage renal disease if not managed effectively. It often presents with few symptoms initially, making regular screening important for at-risk populations such as those with diabetes or hypertension.

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