Histoplasma Capsulatum is a Dimorphic fungus that primarily affects the lungs, causing histoplasmosis, which can range from Mild respiratory symptoms to Severe disseminated disease, especially in Immunocompromised Individuals. It is endemic to certain regions, particularly the Ohio and Mississippi River valleys in the United States, and is transmitted through Inhalation Of Spores found in soil contaminated with bird or bat droppings.