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Heme Oxygenase-1
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Summary
Heme Oxygenase-1
(HO-1) is an enzyme that plays a crucial role in the
Catabolism of heme
into biliverdin,
Free iron
, and
Carbon Monoxide
, exhibiting cytoprotective, anti-inflammatory, and
Antioxidant Properties
. Its upregulation is a
Cellular Response
to
Oxidative Stress
and has
Therapeutic Potential
in various
Pathological Conditions
, including
Cardiovascular Diseases
and
Organ Transplantation
.
Concepts
Heme Catabolism
Biliverdin
Carbon Monoxide
Oxidative Stress
Cytoprotection
Anti-inflammatory Response
Antioxidant Defense
Gene Expression Regulation
Cellular Stress Response
Therapeutic Potential
Free Heme Toxicity
Relevant Degrees
Pathological Physiology 60%
Medicaments According to Origin 40%
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