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Concept
Heme Detoxification
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Summary
Heme Detoxification
is a crucial
Biological Process
that mitigates the
Toxic effects of free heme
, a
Pro-oxidant molecule
released during hemolysis or
Tissue Damage
. This process is vital for maintaining
Cellular Homeostasis
and preventing
Oxidative stress-related damage
in organisms, particularly in parasites like Plasmodium, the
Causative agent of malaria
.
Concepts
Heme Metabolism
Oxidative Stress
Hemozoin Formation
Hemolysis
Plasmodium Biology
Antimalarial Drug Targets
Iron Homeostasis
Enzymatic Detoxification
Hemozoin Inhibition
Relevant Degrees
General Toxicology 60%
Blood and Cardiovascular System 40%
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