The Enhanced Permeability and Retention (EPR) effect is a phenomenon where macromolecular drugs preferentially accumulate in tumor tissue due to the unique vascular architecture of tumors, which allows larger molecules to pass through more easily and be retained longer. This effect is crucial for the design and development of nanoparticle-based drug delivery systems aimed at improving the efficacy and targeting of cancer therapies.

Enhanced Permeability And Retention Effect

Enhanced Permeability and Retention (EPR) effect

macromolecular drugs

tumor tissue

vascular architecture of tumors

larger molecules

Drug delivery systems are engineered technologies for the targeted delivery and controlled release of therapeutic agents, enhancing the efficacy and safety of treatments. These systems aim to optimize the pharmacokinetics and pharmacodynamics of drugs, improving patient compliance and minimizing side effects.

drug delivery systems

Efficacy of cancer therapies

targeting of cancer therapies

nanoparticle-based drug delivery systems

Your Courses

Your Lessons