Drug distribution refers to the process by which a drug is dispersed throughout the body’s tissues and fluids after entering the systemic circulation. This distribution is influenced by factors such as blood flow, tissue permeability, and the drug's affinity for tissue proteins and lipids.

Drug Distribution

Drug distribution

Systemic circulation is the part of the cardiovascular system responsible for carrying oxygenated blood from the heart to the body and returning deoxygenated blood back to the heart. It is crucial for delivering nutrients and oxygen to tissues and organs while removing waste products like carbon dioxide.

systemic circulation

Blood flow refers to the movement of blood through the circulatory system, driven by the heart's pumping action and regulated by blood vessel constriction and dilation. It is essential for delivering oxygen and nutrients to tissues and organs while removing waste products, maintaining homeostasis and supporting overall health.

blood flow

Tissue permeability refers to the ability of biological tissues to allow the passage of substances, such as gases, nutrients, and drugs, through them. It plays a critical role in physiological processes and drug delivery, influencing how substances are absorbed, distributed, and eliminated in the body.

tissue permeability

drug's affinity for tissue proteins

tissue proteins

Lipids are a diverse group of hydrophobic molecules that play crucial roles in energy storage, cell membrane structure, and signaling. They include fats, oils, waxes, phospholipids, and steroids, each with unique functions and structures essential to biological processes.

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