Coagulation necrosis is a type of cell death typically caused by ischemia or infarction, where the architecture of the tissue remains intact but the cells are dead. It is characterized by the coagulation of proteins and the preservation of cell outlines, often seen in myocardial infarctions and other conditions involving severe hypoxia.

Coagulation Necrosis

Coagulation necrosis

Cell death is a fundamental biological process that can occur through different mechanisms such as apoptosis, necrosis, and autophagy, each playing distinct roles in development, homeostasis, and disease. Understanding these pathways is crucial for developing treatments for diseases where cell death is dysregulated, such as cancer and neurodegenerative disorders.

cell death

Ischemia is a condition characterized by insufficient blood supply to tissues, leading to a shortage of oxygen and nutrients needed for cellular metabolism. It can result from various causes such as blockage of blood vessels and is a critical factor in conditions like heart attacks and strokes.

ischemia

Infarction is the process of tissue death due to inadequate blood supply, often caused by blockage of an artery. This condition is most commonly associated with heart attacks and strokes, where the interruption of blood flow leads to significant tissue damage and loss of function.

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