Androgen sensitivity refers to the body's responsiveness to androgens, which are hormones that play a crucial role in male traits and reproductive activity. Variations in androgen sensitivity can lead to different physiological outcomes, influencing conditions like androgen insensitivity syndrome and affecting the efficacy of hormone therapies.

Androgen Sensitivity

Body's responsiveness to androgens

Hormones are chemical messengers produced by glands in the endocrine system that regulate various physiological processes in the body, including growth, metabolism, and mood. They travel through the bloodstream to target organs and tissues, influencing functions such as reproduction, metabolism, and stress response.

Hormones

Male traits

Reproductive activity

Variations in androgen sensitivity

Physiological outcomes

Androgen insensitivity syndrome (AIS) is a genetic condition where an individual who is genetically male (with one X and one Y chromosome) is resistant to male hormones (androgens), which can result in a female physical appearance or ambiguous genitalia. This condition is caused by mutations in the androgen receptor gene, leading to a spectrum of phenotypic presentations depending on the degree of receptor insensitivity.

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