ADP-glucose pyrophosphorylase is a crucial enzyme in the biosynthesis of starch and glycogen, catalyzing the conversion of glucose-1-phosphate and ATP to ADP-glucose and pyrophosphate. This enzyme is a key regulatory point in carbohydrate metabolism and is allosterically controlled by metabolites such as 3-phosphoglycerate and inorganic phosphate.

ADP-glucose Pyrophosphorylase

Biosynthesis of starch

Biosynthesis of glycogen

Conversion of glucose-1-phosphate

Conversion of ATP

ADP-glucose

Pyrophosphate

Key regulatory point

Carbohydrate metabolism involves the biochemical processes responsible for the formation, breakdown, and interconversion of carbohydrates in living organisms. It is crucial for energy production, as carbohydrates are the primary source of energy for most cells, particularly in the form of glucose.

Carbohydrate Metabolism

Allosterically controlled

Metabolites are small molecules that are intermediates and products of metabolism, playing critical roles in various biological processes. They are essential for growth, development, and homeostasis in living organisms, and their study is crucial for understanding disease mechanisms and developing therapeutic strategies.

Metabolites

3-Phosphoglycerate is an important intermediate in both glycolysis and the Calvin cycle in photosynthesis, playing a critical role in the metabolic pathways that transform energy and carbon for cellular processes. It serves as a phosphorylated three-carbon sugar, which acts as a precursor in the biosynthesis of key biomolecules, linking energy capture and conversion systems in living organisms.

Concepts

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