Tau protein pathology refers to the abnormal aggregation of tau proteins in the brain, leading to neurodegenerative diseases such as Alzheimer's. This pathology is characterized by the formation of neurofibrillary tangles, which disrupt neuronal function and contribute to cognitive decline.

Tau Protein Pathology

Abnormal aggregation of tau proteins

Neurodegenerative diseases are a diverse group of disorders characterized by progressive degeneration of the structure and function of the nervous system, often leading to debilitating symptoms and a decline in cognitive and motor functions. These diseases, including Alzheimer's, Parkinson's, and ALS, are typically associated with aging, and their exact causes and mechanisms remain subjects of intensive research, focusing on genetic, environmental, and molecular factors.

Neurodegenerative Diseases

Alzheimer's

Formation of neurofibrillary tangles

Disrupt neuronal function

Cognitive decline refers to the gradual deterioration of cognitive abilities, including memory, reasoning, and problem-solving skills, often associated with aging or neurological disorders. It can significantly impact daily functioning and quality of life, making early detection and intervention crucial for managing its effects.

Concepts

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