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New Course
Concept
T-cell Anergy
T-cell anergy
is a
state of T-cell non-responsiveness
that occurs when T-cells are activated without the necessary
co-stimulatory signals
, preventing them from
attacking the body's own tissues
and contributing to
immune tolerance
. This mechanism is crucial for maintaining self-tolerance and
preventing autoimmune diseases
, but can also be exploited by tumors to evade immune surveillance.
Relevant Degrees
Special Pathology 100%
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