The SWI/SNF complex is a chromatin remodeling complex that uses ATP hydrolysis to reposition nucleosomes, thereby regulating access to DNA for transcription, replication, and repair. It plays a critical role in gene expression and is often mutated in various cancers, highlighting its importance in maintaining genomic stability and proper cellular function.

SWI/SNF Complex

SWI/SNF complex

chromatin remodeling complex

ATP hydrolysis is the process by which adenosine triphosphate (ATP) is broken down into adenosine diphosphate (ADP) and inorganic phosphate, releasing energy that is used by cells to perform various functions. This reaction is critical for cellular processes such as muscle contraction, nerve impulse propagation, and chemical synthesis.

ATP hydrolysis

nucleosomes

regulating access to DNA

Transcription is the biological process where the DNA sequence of a gene is copied into RNA, which serves as a template for protein synthesis. This crucial step in gene expression is regulated by various factors ensuring that the right genes are expressed at the right time and in the right amount.

transcription

Replication is the process of duplicating or reproducing an experiment or study to verify its results and ensure reliability and validity. It is a cornerstone of the scientific method, providing a mechanism for error checking and reinforcing the credibility of research findings.

replication

Repair is the process of restoring a system, object, or structure to a state of functionality or original condition after damage or wear. It involves diagnosing the issue, sourcing necessary materials or parts, and implementing a solution to extend the lifespan and utility of the item in question.

repair

Gene expression is the process by which information from a gene is used to synthesize a functional gene product, typically proteins, which ultimately determine cellular function and phenotype. This process is tightly regulated at multiple levels, including transcription, RNA processing, translation, and post-translational modifications, to ensure proper cellular function and response to environmental cues.

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