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Concept
Pyroptosis
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Summary
Pyroptosis is a form of
Programmed Cell Death
characterized by
Cell Lysis
and the release of
Pro-inflammatory Cytokines
, playing a crucial role in the
Immune Response
against infections. It is distinct from apoptosis and necrosis, involving the activation of
Inflammatory Caspases
such as caspase-1, which cleave
Gasdermin D
to form
Pores in the cell membrane
.
Concepts
Programmed Cell Death
Inflammatory Caspases
Caspase-1
Gasdermin D
Cytokine Release
Cell Lysis
Innate Immunity
Inflammasome
Pathogen Defense
Pro-inflammatory Response
Caspase-1 Activation
NLRP3
Inflammasomes
Cell Death Pathways
Relevant Degrees
Cell Biology and Cytology 50%
Pathology and Disease 30%
Biochemistry and Molecular Biology 20%
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