Performance bias occurs when there is a systematic error in the measurement of outcomes due to differences in how participants are treated, observed, or evaluated. It can significantly affect the validity of study results, especially in clinical trials where blinding is not properly implemented.
Bias in clinical trials refers to systematic errors that can skew the results and interpretations, potentially leading to incorrect conclusions about a treatment's efficacy or safety. It is crucial to identify and mitigate bias to ensure the validity and reliability of trial outcomes, thereby safeguarding patient care and scientific integrity.