Parafollicular C cells, also known as clear cells, are specialized thyroid cells that produce calcitonin, a hormone involved in calcium homeostasis. These cells play a crucial role in lowering blood calcium levels by inhibiting bone resorption and promoting calcium excretion by the kidneys.

Parafollicular C Cells

Parafollicular C cells

clear cells

specialized thyroid cells

Calcitonin is a hormone produced by the thyroid gland that helps regulate calcium levels in the blood by inhibiting bone resorption and promoting calcium excretion in the kidneys. It plays a crucial role in maintaining calcium homeostasis, particularly in response to elevated blood calcium levels.

calcitonin

hormone involved in calcium homeostasis

lowering blood calcium levels

inhibiting bone resorption

promoting calcium excretion

Calcium homeostasis refers to the regulation of calcium levels in the blood and tissues, a critical process for maintaining physiological functions such as muscle contraction, nerve signaling, and bone health. This balance is primarily controlled by the interplay between the parathyroid hormone, vitamin D, and calcitonin, which modulate calcium absorption, excretion, and storage.

calcium homeostasis

blood calcium levels

Bone resorption is a physiological process where osteoclasts break down bone tissue, releasing minerals into the bloodstream and playing a crucial role in bone remodeling and calcium homeostasis. Disruption in this process can lead to conditions such as osteoporosis, where bone density is significantly reduced, increasing fracture risk.

bone resorption

calcium excretion

The kidneys are vital organs responsible for filtering waste products and excess fluids from the blood, maintaining electrolyte balance, and regulating blood pressure. They play a crucial role in overall homeostasis and are essential for the body's detoxification processes and fluid management.

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