Minimal Residual Disease (MRD) refers to the small number of cancer cells that may remain in a patient's body after treatment and are below the detection threshold of traditional diagnostic methods. Detecting and monitoring MRD is crucial for assessing the risk of relapse and tailoring personalized treatment strategies in hematological malignancies and some solid tumors.

Minimal Residual Disease

Cancer cells are like bad guys in the body that don't follow the rules and keep growing when they shouldn't. They can form lumps called tumors and sometimes spread to other parts of the body, making people sick.

cancer cells

Treatment refers to the management and care of a patient to combat disease or disorder, involving various methods tailored to the individual's condition. It encompasses a wide range of strategies, from medication and surgery to therapy and lifestyle changes, with the ultimate goal of improving health outcomes.

treatment

The detection threshold is the minimum level of stimulus intensity that an organism can detect 50% of the time, serving as a critical measure in sensory perception studies. It varies among individuals and can be influenced by factors such as adaptation, attention, and environmental conditions.

detection threshold

traditional diagnostic methods

monitoring MRD

risk of relapse

personalized treatment strategies

Hematological malignancies are cancers that affect the blood, bone marrow, and lymph nodes, originating from the abnormal proliferation of hematopoietic cells. These malignancies are categorized into three main types: leukemia, lymphoma, and myeloma, each with distinct characteristics, treatment approaches, and prognoses.

hematological malignancies

Solid tumors are abnormal masses of tissue that typically arise from the uncontrolled growth of cells in organs or tissues, distinguishing them from blood-related cancers like leukemias. They can be benign, meaning non-cancerous, or malignant, indicating cancerous growths that can invade nearby tissues and metastasize to distant body parts.

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