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Concept
Frameshift Mutation
A
frameshift mutation
is a
genetic mutation
caused by
insertions or deletions
of
nucleotides in DNA sequences
that are not in multiples of three, leading to a shift in the
reading frame
and potentially resulting in a completely
different translation
from the original. This type of mutation can have
severe consequences
, often resulting in
nonfunctional proteins
or diseases such as
cystic fibrosis
and
certain cancers
.
Relevant Degrees
Genetics and Cytogenetics 100%
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