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Fetal Hemoglobin
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Summary
Fetal Hemoglobin
(HbF) is the primary
Oxygen-carrying protein
in the fetus, which has a higher
Affinity for oxygen
than
Adult Hemoglobin
, allowing efficient
Transfer of oxygen
from the mother to the fetus. After birth, HbF is gradually replaced by
Adult Hemoglobin
types, but
Persistence of HbF
can be beneficial in certain hemoglobinopathies like
Sickle Cell Disease
and beta-thalassemia.
Concepts
Hemoglobin
Oxygen Affinity
Hemoglobin Switching
Fetal Development
Sickle Cell Disease
Beta-thalassemia
Erythropoiesis
Hematopoiesis
Globin Gene Expression
Oxygen Transport
Hydroxyurea Therapy
Fetal Red Blood Cells
Fetal Oxygenation
Oxygen Transport In Pregnancy
Relevant Degrees
Blood and Cardiovascular System 88%
Pathology of the Circulatory System 13%
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