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Concept
CSF Circulation
Cerebrospinal fluid (CSF) circulation is a crucial process that involves the production, flow, and absorption of CSF within the
brain's ventricular system
and the
subarachnoid space
surrounding the brain and spinal cord. This circulation maintains
intracranial pressure
, provides
cushioning for the brain
, and removes metabolic waste, playing a vital role in
central nervous system homeostasis
.
Relevant Fields:
Nervous System and Sensory Organs 88%
Neurology 13%
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Concept
Choroid Plexus
The
choroid plexus
is a
network of cells
located in the
ventricles of the brain
that produces
cerebrospinal fluid
, which
cushions the brain and spinal cord
while also
removing waste
. It plays a crucial role in
maintaining the brain's environment
and is involved in the
blood-brain barrier
and
immune surveillance
within the
central nervous system
.
Concept
Ventricular System
The
ventricular system
is a
network of interconnected cavities
within the brain that produce and circulate
cerebrospinal fluid
, which
cushions and protects the brain
and
spinal cord
. This system is crucial for maintaining the
brain's chemical environment
and
removing waste products
.
Concept
Subarachnoid Space
The
subarachnoid space
is a
fluid-filled cavity
located between the
arachnoid mater
and the
pia mater
in the
central nervous system
, playing a crucial role in
protecting the brain
and
spinal cord
by housing
cerebrospinal fluid
. It also serves as a
conduit for blood vessels
and nerves, facilitating
nutrient exchange
and
waste removal
in
neural tissues
.
Concept
Arachnoid Villi
Arachnoid villi
are
small protrusions
of the
arachnoid mater
into the
dural venous sinuses
, facilitating the transfer of
cerebrospinal fluid
(CSF) from the
subarachnoid space
into the
venous system
. This process is crucial for maintaining proper
CSF pressure
and homeostasis within the
central nervous system
.
Concept
Blood-brain Barrier
The
blood-brain barrier
is a
selective permeability barrier
that protects the
central nervous system
from potentially
harmful substances
in the bloodstream while allowing
essential nutrients
to pass through. It is crucial for maintaining the
brain's stable environment
, but it also poses challenges for
drug delivery
to treat
neurological disorders
.
Concept
Hydrocephalus
Hydrocephalus is a
medical condition
characterized by an
abnormal accumulation
of
cerebrospinal fluid
(CSF) in the
brain's ventricles
, leading to
increased intracranial pressure
and
potential brain damage
. It can be congenital or acquired, and treatment often involves
surgical intervention
to
drain the excess fluid
and
alleviate pressure
.
Concept
Intracranial Pressure
Intracranial pressure
(ICP) is the
pressure within the skull
and thus in the brain tissue and
cerebrospinal fluid
, which can be affected by various factors such as
brain injury
, hemorrhage, or infection. Maintaining
normal ICP
is crucial, as
elevated levels
can lead to
brain damage
or death by compromising
cerebral blood flow
and causing
brain herniation
.
Concept
CSF Production
Concept
CSF Absorption
Concept
Ependymal Cells
Ependymal cells
are a type of
glial cell
that line the
ventricles of the brain
and the
central canal of the spinal cord
, playing a crucial role in the production and
circulation of cerebrospinal fluid
(CSF). They also serve as a
barrier between the CSF and the nervous tissue
, and can be involved in neurogenesis in certain conditions.
Concept
Cerebrospinal Fluid
Cerebrospinal fluid
(CSF) is a clear, colorless
body fluid
found within the brain and
spinal cord
that acts as a cushion to protect the
central nervous system
while also removing
waste products
. It plays a crucial role in maintaining
intracranial pressure
and serves as a medium for
nutrient exchange
between the blood and
nervous tissue
.
Concept
Cerebrospinal Fluid Dynamics
Cerebrospinal fluid (CSF) dynamics involve the production, circulation, and absorption of CSF, which
cushions the brain
and spinal cord while
maintaining homeostasis
in the
central nervous system
. Disruptions in CSF dynamics can lead to conditions such as hydrocephalus, intracranial hypertension, or
spinal fluid leaks
,
impacting neurological health
.
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