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Chronic fatigue is a persistent state of extreme tiredness that does not improve with rest and can significantly impair daily functioning. It is often associated with Chronic fatigue syndrome (CFS), a complex disorder characterized by severe fatigue, sleep abnormalities, pain, and other symptoms that are not alleviated by standard medical treatments.
Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), is a complex, long-term illness characterized by extreme fatigue that worsens with physical or mental activity but does not improve with rest. The exact cause is unknown, and it is often diagnosed by ruling out other conditions, with management focusing on symptom relief and improving quality of life.
Sleep disturbances encompass a range of issues that interfere with the quality, timing, and amount of sleep, leading to impaired daytime functioning and increased risk of health problems. These disturbances can result from various factors, including stress, medical conditions, and lifestyle choices, and often require a multifaceted approach for effective management.
Cognitive dysfunction refers to impairments in mental processes such as memory, attention, language, and problem-solving, often resulting from neurological disorders, psychological conditions, or brain injuries. It can significantly impact daily functioning and quality of life, necessitating comprehensive assessment and tailored interventions for management.
Orthostatic intolerance is a condition characterized by the body's inability to properly regulate blood pressure and blood flow when transitioning from a lying down to a standing position, often leading to dizziness, lightheadedness, or fainting. It is commonly associated with disorders like Postural Orthostatic Tachycardia Syndrome (POTS) and can significantly impact daily activities and quality of life.
Mitochondrial dysfunction refers to the failure of mitochondria to produce adequate energy for cellular function, often leading to a range of diseases and age-related conditions. It is implicated in numerous disorders, including neurodegenerative diseases, metabolic syndromes, and cardiovascular diseases, due to its central role in energy metabolism and apoptosis regulation.
Fibromyalgia is a chronic disorder characterized by widespread musculoskeletal pain, fatigue, and tenderness in localized areas. It is thought to be related to abnormal processing of pain signals in the central nervous system, often coexisting with other conditions like irritable bowel syndrome and depression.
Overtraining Syndrome is a condition characterized by a decline in performance and physiological function due to excessive training without adequate rest and recovery. It can lead to symptoms such as fatigue, mood disturbances, and increased risk of injury, ultimately hindering athletic progress.
Primary Adrenal Insufficiency, also known as Addison's disease, is a rare endocrine disorder where the adrenal glands do not produce sufficient steroid hormones, particularly cortisol and aldosterone. It often presents with symptoms such as fatigue, muscle weakness, weight loss, and low blood pressure, requiring lifelong hormone replacement therapy for management.
Gluten sensitivity, also known as non-celiac Gluten sensitivity, is a condition where individuals experience symptoms similar to celiac disease, such as bloating and fatigue, but without the autoimmune response or intestinal damage. It remains controversial and challenging to diagnose due to the absence of specific biomarkers, often requiring a process of elimination to identify offending foods.
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