Checkpoint inhibition is a form of cancer immunotherapy that blocks proteins used by cancer cells to evade detection by the immune system, thereby enabling T-cells to recognize and attack tumors. This approach has revolutionized cancer treatment, showing significant success in treating various types of cancers, such as melanoma and lung cancer.

Checkpoint Inhibition

Checkpoint inhibition

Cancer immunotherapy harnesses the body's immune system to recognize and destroy cancer cells, offering a targeted approach that can result in fewer side effects compared to traditional treatments like chemotherapy and radiation. It includes various strategies such as checkpoint inhibitors, CAR T-cell therapy, and cancer vaccines, each designed to enhance the immune system's natural ability to fight cancer.

cancer immunotherapy

proteins used by cancer cells

evade detection

The immune system is a complex network of cells, tissues, and organs that work together to defend the body against harmful pathogens and maintain overall health. It involves both innate and adaptive responses, which recognize and neutralize foreign invaders while also retaining memory for faster future responses.

immune system

T-cells are a type of lymphocyte that play a central role in cell-mediated immunity, identifying and destroying infected cells and coordinating the immune response. They originate in the bone marrow and mature in the thymus, differentiating into various subtypes with distinct functions in immune defense.

T-cells

recognize and attack tumors

Cancer treatment involves a variety of strategies aimed at eradicating cancer cells, controlling their growth, or alleviating symptoms. These treatments can include surgery, chemotherapy, radiation therapy, immunotherapy, and targeted therapy, among others, and are often used in combination to maximize effectiveness.

cancer treatment

Melanoma is a type of skin cancer that originates in the melanocytes, the cells responsible for pigment production, and is known for its aggressive nature and high potential to metastasize. Early detection and treatment are crucial for improving survival rates, with methods such as the ABCDE rule aiding in the identification of suspicious moles or skin changes.

melanoma

Lung cancer is a malignant lung tumor characterized by uncontrolled cell growth in the tissues of the lung, which can spread to other parts of the body if not treated. It is primarily caused by smoking, but can also result from exposure to radon gas, asbestos, and other carcinogens, as well as genetic factors.

CUSTOMIZE YOUR LEARNING

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