The Antigonid Dynasty was a Hellenistic dynasty that ruled Macedonia and parts of Greece from 306 to 168 BCE, founded by Antigonus I Monophthalmus and his descendants after the fragmentation of Alexander the Great's empire. It played a crucial role in the political and military landscape of the Hellenistic period, contending with other successor states like the Ptolemies and Seleucids until its eventual conquest by the Romans.