The therapeutic index is a ratio that compares the toxic dose of a drug to its effective dose, providing a measure of drug safety. A larger therapeutic index indicates a greater margin between effective and toxic doses, suggesting a safer drug profile.

Therapeutic Index

therapeutic index

A toxic dose refers to the quantity of a substance that produces harmful effects in an organism. Determining the toxic dose is crucial for assessing the safety and risk associated with exposure to chemicals and drugs.

toxic dose

Effective dose is a measure used in radiological protection to account for the risk of exposure to ionizing radiation, considering both the type of radiation and the sensitivity of different tissues and organs. It is expressed in sieverts (Sv) and helps in comparing the potential biological effects of different radiation exposures on human health.

effective dose

measure of drug safety

larger therapeutic index

greater margin

effective and toxic doses

safer drug profile

Introduction to Medication Fundamentals

Formulating Effective Dosages and Combinations

Factors Influencing Biological Responses

Therapeutic Window

Relevant Degrees

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