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Immune Senescence
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Summary
Immune Senescence
refers to the
Gradual deterioration of the immune system
associated with aging, leading to
Increased susceptibility to infections
,
Reduced vaccine efficacy
, and a higher incidence of
Age-Related Diseases
. This process involves complex changes in both innate and
Adaptive Immunity
, characterized by a
Decline in the production of new immune cells
and an
Accumulation of dysfunctional immune cells
.
Concepts
Aging
Innate Immunity
Adaptive Immunity
Thymic Involution
T Cell Exhaustion
Inflammaging
Cytokine Dysregulation
Immunological Memory
B Cell Senescence
Natural Killer Cell Dysfunction
Vaccine Efficacy
Chronic Inflammation
Waning Immunity
Aging-related Inflammation
Relevant Degrees
Pathological Physiology 100%
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